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Terutroban

CAS No. 165538-40-9

Terutroban( S-18886 )

Catalog No. M12526 CAS No. 165538-40-9

Terutroban (S-18886) is a potent, selective antagonist of the thromboxane receptor (Prostanoid TP receptor) that blocks thromboxane induced platelet aggregation and vasoconstriction.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Terutroban
  • Note
    Research use only, not for human use.
  • Brief Description
    Terutroban (S-18886) is a potent, selective antagonist of the thromboxane receptor (Prostanoid TP receptor) that blocks thromboxane induced platelet aggregation and vasoconstriction.
  • Description
    Terutroban (S-18886) is a potent, selective antagonist of the thromboxane receptor (Prostanoid TP receptor) that blocks thromboxane induced platelet aggregation and vasoconstriction.Atherosclerosis Phase 3 Clinical.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    S-18886
  • Pathway
    GPCR/G Protein
  • Target
    Prostaglandin Receptor
  • Recptor
    Prostaglandin Receptor
  • Research Area
    Cardiovascular Disease
  • Indication
    Atherosclerosis

Chemical Information

  • CAS Number
    165538-40-9
  • Formula Weight
    407.911
  • Molecular Formula
    C20H22ClNO4S
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: ≥ 22 mg/mL
  • SMILES
    O=C(O)CCC1=C2CC[C@@H](NS(=O)(C3=CC=C(Cl)C=C3)=O)CC2=CC=C1C
  • Chemical Name
    1-Naphthalenepropanoic acid, 6-[[(4-chlorophenyl)sulfonyl]amino]-5,6,7,8-tetrahydro-2-methyl-, (6R)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gaussem P, et al. J Thromb Haemost. 2005 Jul;3(7):1437-45. 2. Xu S, et al. Diabetes. 2006 Jan;55(1):110-9. 3. Simonet S, et al. Adv Exp Med Biol. 1997;433:173-6.
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