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Home - Products - Apoptosis - MDM2-p53 - UNC-2170

UNC-2170

CAS No. 1648707-58-7

UNC-2170( UNC2170 )

Catalog No. M12518 CAS No. 1648707-58-7

UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 61 Get Quote
5MG 102 Get Quote
10MG 170 Get Quote
25MG 372 Get Quote
50MG 556 Get Quote
100MG 791 Get Quote
500MG 1611 Get Quote
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Biological Information

  • Product Name
    UNC-2170
  • Note
    Research use only, not for human use.
  • Brief Description
    UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain.
  • Description
    UNC-2170 is a small molecule ligand for the methyl-lysine binding protein 53BP1 (p53-binding protein 1) with Kd of 22 uM against the 53BP1 tandem tudor domain; is highly cell permeant with no significant measureable cellular efflux; shows modestly potent, demonstrates at least 17-fold selectivity for 53BP1 as compared to nine other Kme reader proteins.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    UNC2170
  • Pathway
    Apoptosis
  • Target
    MDM2-p53
  • Recptor
    MDM2-p53
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1648707-58-7
  • Formula Weight
    313.23
  • Molecular Formula
    C14H21BrN2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?Methanol : 125 mg/mL (399.07 )
  • SMILES
    CC(C)(C)NCCCNC(=O)C1=CC(=CC=C1)Br.C(=CC(=O)O)C(=O)O
  • Chemical Name
    3-bromo-N-(3-(tert-butylamino)propyl)benzamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Perfetti MT, et al. ACS Chem Biol. 2015 Apr 17;10(4):1072-81.
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