Esomeprazole Magnesium

Research use only, not for human use.

Esomeprazole Magnesium is a proton pump inhibitor to reduce gastric acid secretion.

Esomeprazole Magnesium is a proton pump inhibitor to reduce gastric acid secretion.(In Vitro):Esomeprazole magnesium is an inhibitor of H+, K+-ATPase.Esomeprazole magnesium is develped from Esomeprazole strontium tetrahydrate (EST). EST contains esomeprazole, the S-enantiomer of omeprazole a salt-exchanged version of Esomeprazole magnesium trihydrate.(In Vivo):Esomeprazole magnesium (0.5-50 mg/kg; oral gavage; daily; for 10 days; A/J mice) treatment increases gastric total antioxidant capacity and Cu/Zn-superoxide dismutase activity.

Esomeprazole magnesium is an inhibitor of H+, K+-ATPase.Esomeprazole magnesium is develped from Esomeprazole strontium tetrahydrate (EST). EST contains esomeprazole, the S-enantiomer of omeprazole a salt-exchanged version of Esomeprazole magnesium trihydrate.

Esomeprazole magnesium (0.5-50 mg/kg; oral gavage; daily; for 10 days; A/J mice) treatment increases gastric total antioxidant capacity and Cu/Zn-superoxide dismutase activity. Animal Model:A/J mice Dosage:0.5 mg/kg, 5 mg/kg, 50 mg/kg Administration:Oral gavage; daily; for 10 days Result:Gastric total antioxidant capacity and Cu/Zn-superoxide dismutase activity are increased.

(S)-Omeprazole

Endocrinology/Hormones

ATPase

H+/K+-ATPase

Other Indications

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161973-10-0

713.12

C34H36MgN6O6S2

>98% (HPLC)

Ethanol: 143 mg/mL (200.52 mM); DMSO: 143 mg/mL (200.52 mM)

CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.[Mg+2]

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(-20℃)

With Ice Pack

≥ 2 years