IDX-17119( IDX17119 )

Catalog No. M13106 CAS No. 1987906-92-2

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

IDX-17119
Note

Research use only, not for human use.
Brief Description

IDX-17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assay.
Description

IDX-17119 is a potent, non-nucleoside, HCV NS5B RdRp inhibitor with IC50 of 0.4 nM in replicon luciferase assay; shows activity against broad genotype profile: IC50= 0.0099 uM, 0.2538 uM, 0.1809 uM and 0.0257 uM on genotypes 1b, 2a, 3a and 4a, respectively.
In Vitro

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In Vivo

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Synonyms

IDX17119
Pathway

Microbiology/Virology
Target

HCV
Recptor

HCV
Research Area

——
Indication

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CAS Number

1987906-92-2
Formula Weight

531.513
Molecular Formula

C26H26N7O4P
Purity

>98% (HPLC)
Solubility

——
SMILES

CC1=CC(=C(C=C1)P(=O)(NC2=NN(C=C2C(=O)O)C3=CC=C(C=C3)C4=NN5C(=CC(=NC5=C4)C)N)OC)C
Chemical Name

1-(4-(7-amino-5-methylpyrazolo[1,5-a]pyrimidin-2-yl)phenyl)-3-(((2,4-dimethylphenyl)(methoxy)phosphoryl)amino)-1H-pyrazole-4-carboxylic acid

1. Pierra Rouvière C, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4536-41.

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