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HBX 28258
CAS No. 1426544-54-8
HBX 28258( HBX28258 )
Catalog No. M11801 CAS No. 1426544-54-8
HBX 28258 is a potent, selective USP7 inhibitor with IC50 of 22.6 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameHBX 28258
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NoteResearch use only, not for human use.
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Brief DescriptionHBX 28258 is a potent, selective USP7 inhibitor with IC50 of 22.6 uM.
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DescriptionHBX 28258 is a potent, selective USP7 inhibitor with IC50 of 22.6 uM, exhibits high selectivity over other USP members, such as USP8, USP5, USP2, and USP20 (IC50 >200 uM), and no activity against UCH-L1, UCH-L3 and SENP1; reduces HCT116 cell proliferation, induces caspase activity and PARP cleavage, and arrestes HCT116 cancer cells in G1 phase.
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In Vitro——
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In Vivo——
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SynonymsHBX28258
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PathwayProteasome/Ubiquitin
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TargetDUB
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RecptorDUB
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Research Area——
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Indication——
Chemical Information
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CAS Number1426544-54-8
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Formula Weight435.996
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Molecular FormulaC26H30ClN3O
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=CC2=C(Cl)C3=C(CCCC3)N=C2C=C1)NCCCN(CC)CC4=CC=CC=C4
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Chemical Name2-Acridinecarboxamide, 9-chloro-N-[3-[ethyl(phenylmethyl)amino]propyl]-5,6,7,8-tetrahydro-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Reverdy C, et al. Chem Biol. 2012 Apr 20;19(4):467-77.
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