Cart
sales@molnova.com
HBX 28258
CAS No. 1426544-54-8
HBX 28258( HBX28258 )
Catalog No. M11801 CAS No. 1426544-54-8
HBX 28258 is a potent, selective USP7 inhibitor with IC50 of 22.6 uM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameHBX 28258
-
NoteResearch use only, not for human use.
-
Brief DescriptionHBX 28258 is a potent, selective USP7 inhibitor with IC50 of 22.6 uM.
-
DescriptionHBX 28258 is a potent, selective USP7 inhibitor with IC50 of 22.6 uM, exhibits high selectivity over other USP members, such as USP8, USP5, USP2, and USP20 (IC50 >200 uM), and no activity against UCH-L1, UCH-L3 and SENP1; reduces HCT116 cell proliferation, induces caspase activity and PARP cleavage, and arrestes HCT116 cancer cells in G1 phase.
-
In Vitro——
-
In Vivo——
-
SynonymsHBX28258
-
PathwayProteasome/Ubiquitin
-
TargetDUB
-
RecptorDUB
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1426544-54-8
-
Formula Weight435.996
-
Molecular FormulaC26H30ClN3O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C(C1=CC2=C(Cl)C3=C(CCCC3)N=C2C=C1)NCCCN(CC)CC4=CC=CC=C4
-
Chemical Name2-Acridinecarboxamide, 9-chloro-N-[3-[ethyl(phenylmethyl)amino]propyl]-5,6,7,8-tetrahydro-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Reverdy C, et al. Chem Biol. 2012 Apr 20;19(4):467-77.
molnova catalog
related products
-
USP28-IN-3
USP28-IN-3 is a highly selective USP28 inhibitor with an IC50 value of 0.1 μM against USP28.USP28-IN-3 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3, and UCHL5.
-
Spautin-1 (b)
Spautin-1 is a potent, small molecule inhibitor of autophagy with IC50 of 0.74 uM.
-
USP7-IN-8
USP7-IN-8 is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM. USP7-IN-8 has anticancer effects.
