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MM-102
CAS No. 1417329-24-8
MM-102( MM102 | MM 102 )
Catalog No. M11741 CAS No. 1417329-24-8
A high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 42 | In Stock |
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| 5MG | 96 | In Stock |
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| 10MG | 159 | In Stock |
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| 25MG | 333 | In Stock |
|
| 50MG | 515 | In Stock |
|
| 100MG | 736 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameMM-102
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NoteResearch use only, not for human use.
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Brief DescriptionA high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM.
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DescriptionA high-affinity, small-molecule peptidomimetic inhibitor of MLL1/WDR5 protein-protein interaction with Ki of 2.4 nM; effectively decreases the expression of HoxA9 and Meis-1; specifically inhibits cell growth and induces apoptosis in leukemia cells harboring MLL1 fusion proteins.
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In Vitro——
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In Vivo——
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SynonymsMM102 | MM 102
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PathwayChromatin/Epigenetic
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TargetHMTase
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RecptorMLL1
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1417329-24-8
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Formula Weight669.8049
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Molecular FormulaC35H49F2N7O4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESO=C(C1(NC([C@@H](NC(C(NC(C(C)C)=O)(CC)CC)=O)CCC/N=C(N)/N)=O)CCCC1)NC(C2=CC=C(F)C=C2)C3=CC=C(F)C=C3
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Chemical NameCyclopentanecarboxamide, 1-[[(2S)-5-[(aminoiminomethyl)amino]-2-[[2-ethyl-2-[(2-methyl-1-oxopropyl)amino]-1-oxobutyl]amino]-1-oxopentyl]amino]-N-[bis(4-fluorophenyl)methyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Karatas H, et al. J Am Chem Soc. 2013 Jan 16;135(2):669-82.
molnova catalog
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