CN-SAH

CAS No. 1985669-27-9

CN-SAH( —— )

Catalog No. M13103 CAS No. 1985669-27-9

CN-SAH is a potent and selective inhibitor of histone methyl transferase DOT1L with IC50 of 26 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CN-SAH
  • Note
    Research use only, not for human use.
  • Brief Description
    CN-SAH is a potent and selective inhibitor of histone methyl transferase DOT1L with IC50 of 26 nM.
  • Description
    CN-SAH is a potent and selective inhibitor of histone methyl transferase DOT1L with IC50 of 26 nM, displays >10-fold selectivity over DNMT1, PRMT3, PRMT5, and G9α.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    HMTase
  • Recptor
    HMTase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1985669-27-9
  • Formula Weight
    408.433
  • Molecular Formula
    C16H20N6O5S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    S-(((2S,3R,4S,5R)-5-(4-amino-5-cyano-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)-L-homocysteine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Spurr SS, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4518-22.
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