myomiRs-IN-1( myomiR-IN-1 | myomiR IN 1 | myomiRIN1 | myomiR inhibitor-1 )

Catalog No. M11630 CAS No. 1392224-59-7

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

myomiRs-IN-1
Note

Research use only, not for human use.
Brief Description

myomiRs-IN-1 is a small-molecule probe that selectively inhibits myogenic microRNAs (myomiRs) including miR-1, miR-133a, and miR-206.
Description

myomiRs-IN-1 is a small-molecule probe that selectively inhibits myogenic microRNAs (myomiRs) including miR-1, miR-133a, and miR-206; upregulates miR-221/222 level and suppresses myoD protein expression in C2C12 cells; inhibits the differentiation of C2C12 cells.
In Vitro

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In Vivo

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Synonyms

myomiR-IN-1 | myomiR IN 1 | myomiRIN1 | myomiR inhibitor-1
Pathway

Chromatin/Epigenetic
Target

MicroRNA
Recptor

MicroRNA
Research Area

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Indication

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CAS Number

1392224-59-7
Formula Weight

533.58
Molecular Formula

C33H27NO6
Purity

>98% (HPLC)
Solubility

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SMILES

O=C(C1=C2C=CC=C1)C(C(C3=C4C=CC=NC4=C(OC(OC(C)(C)C)=O)C=C3)=C5C6=CC=CC=C6)(OC)C5C2=O
Chemical Name

tert-butyl (5-(8a-methoxy-3,8-dioxo-2-phenyl-2a,3,8,8a-tetrahydrocyclobuta[b]naphthalen-1-yl)quinolin-8-yl) carbonate

1. Tan SB, et al. Chem Biol. 2014 Oct 23;21(10):1265-70.

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