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25CN-NBOH
CAS No. 1391489-32-9
25CN-NBOH( 25CN NBOH )
Catalog No. M11623 CAS No. 1391489-32-9
A potent, highly selective and brain-penetrant 5-HT2A receptor agonist with Ki of 1.1 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name25CN-NBOH
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NoteResearch use only, not for human use.
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Brief DescriptionA potent, highly selective and brain-penetrant 5-HT2A receptor agonist with Ki of 1.1 nM.
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DescriptionA potent, highly selective and brain-penetrant 5-HT2A receptor agonist with Ki of 1.1 nM ([3H]ketanserin); >100-fold over 5-HT2CR and 46-fold selectivity over 5-HT2BR; exhibits 30- to 180-fold 5-HT2A/5-HT2C selectivities and 54-fold 5-HT2A/5-HT2B selectivity in inositol phosphate and intracellular Ca2+ mobilization assays; is a superior selective and brain-penetrant 5-HT2A receptor agonist compared with (±)-2,5-dimethoxy-4-iodoamphetamine (DOI).
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In Vitro——
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In Vivo——
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Synonyms25CN NBOH
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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Recptor5-HT Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1391489-32-9
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Formula Weight312.369
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Molecular FormulaC18H20N2O3
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Purity>98% (HPLC)
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Solubility——
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SMILESCOC1=CC(=C(C=C1CCNCC2=CC=CC=C2O)OC)C#N.Cl
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Chemical Name2-([2-(4-cyano-2,5-dimethoxyphenyl) ethylamino]methyl)phenol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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5,6,7-TRIMETHOXYFLAV...
5,6,7-Trimethoxyflavone is a novel?p38-α MAPK?inhibitor with an anti-inflammatory effect. 5,6,7-Trimethoxyflavone is isolated from several?plants?including?Zeyhera tuberculosa,?Callicarpa japonica, and?Kickxia lanigera.
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PF-03246799
A potent and selective 5-HT2C receptor agonist with EC50 of 190 nM, with excellent selectivity for 5-HT2C over 5-HT2A.
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Homoeriodictyol
Homoeriodictyol, a naturally occurring, bitter-masking flavanone, as a promising agent to increase appetite and food intake. The flavanone homoeriodictyol can increase SGLT-1-mediated glucose uptake but decrease serotonin release in differentiated Caco-2 cells.In contrast to other polyphenols, the flavanon Homoeriodictyol promotes glucose uptake by 29.0 ± 3.83% at a concentration of 100 μM.
