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EPZ004777 HCl

CAS No. 1380316-03-9

EPZ004777 HCl ( —— )

Catalog No. M11571 CAS No. 1380316-03-9

EPZ004777 hydrochloride is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

EPZ004777 HCl
Note

Research use only, not for human use.
Brief Description

EPZ004777 hydrochloride is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
Description

EPZ004777 hydrochloride is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Chromatin/Epigenetic
Target

HMTase
Recptor

DOT1L
Research Area

Cancer
Indication

——

Chemical Information

CAS Number

1380316-03-9
Formula Weight

576.13
Molecular Formula

C??H??ClN?O?
Purity

>98% (HPLC)
Solubility

DMSO:Soluble
SMILES

CC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC4=C3N=CN=C4N)O)O.Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Chen L, et al. Leukemia. 2013, 27(4), 813-822.

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