Cart
sales@molnova.com
EPZ004777 HCl
CAS No. 1380316-03-9
EPZ004777 HCl ( —— )
Catalog No. M11571 CAS No. 1380316-03-9
EPZ004777 hydrochloride is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameEPZ004777 HCl
-
NoteResearch use only, not for human use.
-
Brief DescriptionEPZ004777 hydrochloride is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
-
DescriptionEPZ004777 hydrochloride is a potent, selective DOT1L inhibitor with IC50 of 0.4 nM.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayChromatin/Epigenetic
-
TargetHMTase
-
RecptorDOT1L
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1380316-03-9
-
Formula Weight576.13
-
Molecular FormulaC??H??ClN?O?
-
Purity>98% (HPLC)
-
SolubilityDMSO:Soluble
-
SMILESCC(C)N(CCCNC(=O)NC1=CC=C(C=C1)C(C)(C)C)C[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=CC4=C3N=CN=C4N)O)O.Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Chen L, et al. Leukemia. 2013, 27(4), 813-822.
molnova catalog
related products
-
MS0124
MS-0124 is a potent and selective inhibitor of G9a-like Protein (GLP) lysine methyltransferase with IC50 of 13 nM.
-
MI-503
A highly potent and orally bioavailable small-molecule inhibitor of Menin-MLL interaction with Kd of 9.3 nM.
-
TP-064
TP-064 is a potent, selective, and cell-active inhibitor of PRMT4 with IC50 of <10 nM and Kd of 7.1 nM.
