DMJ-I-228( +)-DMJ-I-228 )

Catalog No. M11542 CAS No. 1374035-59-2

A small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
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50MG	1782	Get Quote
100MG	2250	Get Quote
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Biological Information

Product Name

DMJ-I-228
Note

Research use only, not for human use.
Brief Description

A small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.
Description

A small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.
In Vitro

——
In Vivo

——
Synonyms

+)-DMJ-I-228
Pathway

Microbiology/Virology
Target

HIV
Recptor

HIV
Research Area

——
Indication

——

Chemical Information

CAS Number

1374035-59-2
Formula Weight

435.84
Molecular Formula

C19H19ClFN5O4
Purity

>98% (HPLC)
Solubility

——
SMILES

O=C(NC1=CC=C(Cl)C(F)=C1)C(N[C@@H]2[C@@H](NC(N)=N)CC3=C2C=CC=C3)=O.O=CO
Chemical Name

N1-(4-chloro-3-fluorophenyl)-N2-((1S,2S)-2-guanidino-2,3-dihydro-1H-inden-1-yl)oxalamide formate

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Madani N, et al. Structure. 2008 Nov 12; 16(11):1689-701. 2. Richard J, et al. Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2687-94. 3. LaLonde JM, et al. J Med Chem. 2012 May 10;55(9):4382-96.

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