Cart
sales@molnova.com
SHR3824
CAS No. 1358579-22-2
SHR3824( SHR 3824 | SHR-3824 )
Catalog No. M11472 CAS No. 1358579-22-2
SHR3824 is a potent, selective SGLT2 inhibitor with IC50 of 2.38 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameSHR3824
-
NoteResearch use only, not for human use.
-
Brief DescriptionSHR3824 is a potent, selective SGLT2 inhibitor with IC50 of 2.38 nM.
-
DescriptionSHR3824 is a potent, selective SGLT2 inhibitor with IC50 of 2.38 nM, >1000-fold selectivity over SGLT1; exhibits antidiabetic efficacy in several rodent models.Diabetes Phase 1 Clinical.
-
In Vitro——
-
In Vivo——
-
SynonymsSHR 3824 | SHR-3824
-
PathwayGPCR/G Protein
-
TargetSGLT
-
RecptorSGLT
-
Research AreaMetabolic Disease
-
IndicationDiabetes
Chemical Information
-
CAS Number1358579-22-2
-
Formula Weight454.875
-
Molecular FormulaC22H24ClFO7
-
Purity>98% (HPLC)
-
Solubility——
-
SMILES——
-
Chemical Name(1R,2S,3S,4R,5R)-5-(4-Chloro-3-(4-ethoxy-3-fluorobenzyl)phenyl)-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Yan PK, et al. Acta Pharmacol Sin. 2014 May;35(5):613-24. doi: 10.1038/aps.2013.196.
molnova catalog
related products
-
Sergliflozin A
Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.
-
PF-04971729
A potent and selective SGLT2 inhibitor with IC50 of 0.877 nM for hSGLT2.
-
KGA-2727
KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively.?The selectivity ratios (Ki for SGLT2/Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat).?KGA-2727 for the treatment of diabete.KGA-2727, which has a pyrazole-O-glucoside structure, as the first selective SGLT1 inhibitor.?
