DBCO-NHS ester( DBCO NHS ester )

Catalog No. M11436 CAS No. 1353016-71-3

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

DBCO-NHS ester
Note

Research use only, not for human use.
Brief Description

An amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.
Description

An amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine; A click chemistry tool used to conjugate DBCO-PEG4-MMAF to the introduced non-natural amino acid pAMF using a noncleavable linker.
In Vitro

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In Vivo

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Synonyms

DBCO NHS ester
Pathway

Antibody Drug Conjugates (ADC)
Target

ADCs Linker/Click Chemistry
Recptor

ADCs Linker/Click Chemistry
Research Area

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Indication

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CAS Number

1353016-71-3
Formula Weight

430.45
Molecular Formula

C25H22N2O5
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (124.25 mM)
SMILES

O=C(CCC(ON1C(CCC1=O)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
Chemical Name

Dibenz[b,f]azocine-5(6H)-butanoic acid,11,12-didehydro-γ-oxo-,2,5-dioxo-1-pyrrolidinyl es

1. Currier NV, et al. Mol Cancer Ther. 2016 Jun;15(6):1291-300.

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