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DBCO-NHS ester
CAS No. 1353016-71-3
DBCO-NHS ester( DBCO NHS ester )
Catalog No. M11436 CAS No. 1353016-71-3
An amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 28 | Get Quote |
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| 10MG | 46 | Get Quote |
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| 25MG | 77 | Get Quote |
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| 50MG | 114 | Get Quote |
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| 100MG | 200 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameDBCO-NHS ester
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NoteResearch use only, not for human use.
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Brief DescriptionAn amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine.
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DescriptionAn amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine; A click chemistry tool used to conjugate DBCO-PEG4-MMAF to the introduced non-natural amino acid pAMF using a noncleavable linker.
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In Vitro——
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In Vivo——
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SynonymsDBCO NHS ester
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PathwayAntibody Drug Conjugates (ADC)
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TargetADCs Linker/Click Chemistry
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RecptorADCs Linker/Click Chemistry
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Research Area——
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Indication——
Chemical Information
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CAS Number1353016-71-3
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Formula Weight430.45
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Molecular FormulaC25H22N2O5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (124.25 mM)
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SMILESO=C(CCC(ON1C(CCC1=O)=O)=O)N2CC3=C(C=CC=C3)C#CC4=C2C=CC=C4
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Chemical NameDibenz[b,f]azocine-5(6H)-butanoic acid,11,12-didehydro-γ-oxo-,2,5-dioxo-1-pyrrolidinyl es
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Currier NV, et al. Mol Cancer Ther. 2016 Jun;15(6):1291-300.
molnova catalog
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N3-C2-NHS ester
N3-C2-NHS ester (3-Azidopropanoic acid NHS ester) is an ADC linker, which is a cross-linking agent for macromolecular compounds, and can be used for the synthesis of antibody-coupled reactive molecules (ADCs).
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Gly-Gly-Gly-PEG4-DBC...
Gly-Gly-Gly-PEG4-DBCO is a degradable ADC linker containing 4 units of PEG, which can be used to synthesize antibody-conjugated active molecules (ADCs).
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DSS Crosslinker
DSS Crosslinker is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).It is a homobifunctional crosslinker that is cell membrane permeable. DSS crosslinker has amine-reactive NHS esters at both ends of an 8-atom (11.4 angstrom) spacer arm that are used to conjugate proteins.
