Batimastat ( BB-94 )

Catalog No. M11219 CAS No. 130370-60-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Batimastat
Note

Research use only, not for human use.
Brief Description

Batimastat (BB-94) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3 with IC50 of 3 nM, 4 nM, 4 nM, 6 nM and 20 nM, respectively.
Description

Batimastat (BB-94) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3 with IC50 of 3 nM, 4 nM, 4 nM, 6 nM and 20 nM, respectively. Also inhibits the activitity of other metalloproteases, such as ADAM17.
In Vitro

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In Vivo

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Synonyms

BB-94
Pathway

Metabolic Enzyme/Protease
Target

MMP
Recptor

MMP-1| MMP-2| MMP-3| MMP-7| MMP-9
Research Area

Cancer
Indication

——

CAS Number

130370-60-4
Formula Weight

477.64
Molecular Formula

C23H31N3O4S2
Purity

>98% (HPLC)
Solubility

DMSO:96 mg/mL (200.98 mM); Ethanol:<1 mg/mL (<1 mM); Water：<1 mg/mL (<1 mM)
SMILES

CNC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H](CC(C)C)[C@H](CSC1=CC=CS1)C(=O)NO |r,c:8,10,26,t:6,24|
Chemical Name

——

1. Chirivi RG, et al. Int J Cancer, 1994, 58(3), 460-464.

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