Cart
sales@molnova.com
Levocetirizine
CAS No. 130018-77-8
Levocetirizine( Levocetirizine | Xarlin | Xusal )
Catalog No. M11207 CAS No. 130018-77-8
Levocetirizine is a Histamine-1 Receptor Antagonist. The mechanism of action of levocetirizine is as a Histamine H1 Receptor Antagonist.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 33 | In Stock |
|
| 5MG | 30 | In Stock |
|
| 10MG | 54 | In Stock |
|
| 25MG | 78 | In Stock |
|
| 50MG | 90 | In Stock |
|
| 100MG | 169 | In Stock |
|
| 200MG | 252 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameLevocetirizine
-
NoteResearch use only, not for human use.
-
Brief DescriptionLevocetirizine is a Histamine-1 Receptor Antagonist. The mechanism of action of levocetirizine is as a Histamine H1 Receptor Antagonist.
-
DescriptionLevocetirizine is a Histamine-1 Receptor Antagonist. The mechanism of action of levocetirizine is as a Histamine H1 Receptor Antagonist. (In Vivo):Levocetirizine (0.4 mg/kg; oral administration; male Sprague-Dawley rats) treatment shows that the Cmax, AUC0-t, AUC0-∞ and t1/2 are 0.34 μg/mL, 3.26 μg h/mL, 3.67 μg h/mL and 2.34 hours, respectively in Sprague-Dawley rats.
-
In Vitro——
-
In VivoLevocetirizine (0.4 mg/kg; oral administration; male Sprague-Dawley rats) treatment shows that the Cmax, AUC0-t , AUC0-∞ and t1/2 are 0.34 μg/mL, 3.26 μg h/mL, 3.67 μg h/mL and 2.34 hours, respectively in Sprague-Dawley rats. Animal Model:30 male Sprague-Dawley rats (8 weeks old; 200-250 g) Dosage:0.4 mg/kg Administration:Oral administration (Pharmacokinetic Analysis)Result:The Cmax, AUC0-t , AUC0-∞ and t1/2 were 0.34 μg/mL, 3.26 μg h/mL, 3.67 μg h/mL and 2.34 hours, respectively.
-
SynonymsLevocetirizine | Xarlin | Xusal
-
PathwayGPCR/G Protein
-
TargetHistamine Receptor
-
RecptorH1 receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number130018-77-8
-
Formula Weight388.89
-
Molecular FormulaC21H25ClN2O3
-
Purity>98% (HPLC)
-
SolubilitySoluble in DMSO
-
SMILESOC(=O)COCCN1CCN(CC1)[C@H](c2ccccc2)c3ccc(Cl)cc3
-
Chemical NameAcetic acid, (2-(4-((R)-(4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Pasquali M, et al. Clin Exp Allergy. 2006 Sep;36(9):1161-7.
molnova catalog
related products
-
Ciproxifan maleate
Ciproxifan maleate(FUB-359 maleate) is a highly potent and selective histamin H3-receptor antagonist with IC50 of 9.2 nM, with low apparent affinity at other receptor subtypes.
-
Bavisant
Bavisant is a selective and orally active Human H3 receptor antagonist. Bavisant can be used in research on mechanisms of action, involving wakefulness and cognition and the treatment for ADHD.
-
MK-0249 B
MK-0249 is an orally active, selective and potent histamine H3 receptor antagonist (IC50: 1.7 nM) for the study of attention-deficit and hyperactivity disorders.
