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H4 Receptor antagonist 1
CAS No. 848217-00-5
H4 Receptor antagonist 1( —— )
Catalog No. M20493 CAS No. 848217-00-5
H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist with an IC50 of 19 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 40 | In Stock |
|
| 5MG | 65 | In Stock |
|
| 10MG | 102 | In Stock |
|
| 25MG | 197 | In Stock |
|
| 50MG | 356 | In Stock |
|
| 100MG | 533 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameH4 Receptor antagonist 1
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NoteResearch use only, not for human use.
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Brief DescriptionH4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist with an IC50 of 19 nM.
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DescriptionH4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist with an IC50 of 19 nM.
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In VitroH4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.
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In VivoH4 Receptor antagonist 1 indicates that metabolic stability in rat microsomes is very low with only 1% parent compound remaining after 10 min incubation.
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Synonyms——
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PathwayGPCR/G Protein
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TargetHistamine Receptor
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RecptorH4 receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number848217-00-5
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Formula Weight316.78
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Molecular FormulaC16H17ClN4O
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Purity>98% (HPLC)
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SolubilityDMSO:10 mg/mL (31.57 mM)
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SMILESCN1CCN(CC1)c1nc(C)nc2c3cc(Cl)ccc3oc12
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Cramp S Dyke H J Higgs C et al. Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists[J]. Bioorganic & Medicinal Chemistry Letters 2010 20(8):2516-2519.
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