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PI3K-IN-8q
CAS No. 1280204-67-2
PI3K-IN-8q( —— )
Catalog No. M11155 CAS No. 1280204-67-2
PI3K-IN-8q is a potent, selective dual p110α/p110δ inhibitor with Ki app of 3.3/8.36 nM respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NamePI3K-IN-8q
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NoteResearch use only, not for human use.
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Brief DescriptionPI3K-IN-8q is a potent, selective dual p110α/p110δ inhibitor with Ki app of 3.3/8.36 nM respectively.
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DescriptionPI3K-IN-8q is a potent, selective dual p110α/p110δ inhibitor with Ki app of 3.3/8.36 nM respectively; exhibits high selectivity over p110α and p110β (Ki>490 nM); inhibits p-Akt with EC50 of 50 nM, and p110α with IC50 of 0.5 nM; has promising in vivo PK data; orally bioavailable.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorPI3K
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Research Area——
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Indication——
Chemical Information
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CAS Number1280204-67-2
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Formula Weight446.49
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Molecular FormulaC23H23FN8O
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Purity>98% (HPLC)
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Solubility——
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SMILES——
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Chemical Name5-(2-(4-fluorophenyl)-9-morpholino-1,2,3,4-tetrahydropyrido[3',4':4,5]imidazo[1,2-a]pyrazin-7-yl)pyrimidin-2-amine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Martínez González S, et al. Bioorg Med Chem Lett. 2017 Jun 1;27(11):2536-2543.
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