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RQ00203078
CAS No. 1254205-52-1
RQ00203078( RQ-00203078 | RQ 00203078 | RQ00203078 )
Catalog No. M11029 CAS No. 1254205-52-1
RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist (IC50 values are 5.3 and 8.3 nM for rat and human channels respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
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| 5MG | 41 | In Stock |
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| 10MG | 68 | In Stock |
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| 25MG | 120 | In Stock |
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| 50MG | 183 | In Stock |
|
| 100MG | 343 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRQ00203078
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NoteResearch use only, not for human use.
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Brief DescriptionRQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist (IC50 values are 5.3 and 8.3 nM for rat and human channels respectively).
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DescriptionRQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist (IC50 values are 5.3 and 8.3 nM for rat and human channels respectively), exhibits >350-fold selectivity for TRPM8 over TRPV4, TRPV1 and TRPA1.
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In Vitro——
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In Vivo——
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SynonymsRQ-00203078 | RQ 00203078 | RQ00203078
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PathwayMembrane Transporter/Ion Channel
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TargetTRP/TRPV Channel
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RecptorTRPM8
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1254205-52-1
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Formula Weight554.85
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Molecular FormulaC21H13ClF6N2O5S
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Purity>98% (HPLC)
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SolubilityDMSO: 100 mM
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SMILESO=C(O)C1=CC=C(S(=O)(N(C2=NC=C(C(F)(F)F)C=C2Cl)CC3=CC=C(OC(F)(F)F)C=C3)=O)C=C1
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Chemical Name4-(N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-(trifluoromethoxy)benzyl)sulfamoyl)benzoic acid
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Chaussade C, et al. Biochem J, 2007, 404(3), 449-58.
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