P 22077

CAS No. 1247819-59-5

P 22077( P22077 | P-22077 | P 22077 )

Catalog No. M11000 CAS No. 1247819-59-5

P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 86 In Stock
2MG 30 In Stock
5MG 49 In Stock
10MG 79 In Stock
25MG 159 In Stock
50MG 297 In Stock
100MG 443 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    P 22077
  • Note
    Research use only, not for human use.
  • Brief Description
    P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.
  • Description
    P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM, also inhibits the closely related USP47.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    P22077 | P-22077 | P 22077
  • Pathway
    Proteasome/Ubiquitin
  • Target
    DUB
  • Recptor
    USP2| USP4| USP47| USP5| USP7
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1247819-59-5
  • Formula Weight
    315.32
  • Molecular Formula
    C12H7F2NO3S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 63 mg/mL (199.79 mM)
  • SMILES
    CC(C1=CC([N+]([O-])=O)=C(SC2=CC=C(F)C=C2F)S1)=O
  • Chemical Name
    1-(5-((2,4-difluorophenyl)thio)-4-nitrothiophen-2-yl)ethanone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tian X, et al. Assay Drug Dev Technol, 2011, 9(2), 165-173.
molnova catalog
related products
  • Ubiquitin Isopeptida...

    A small molecule inhibitor of ubiquitin-proteasome system by inhibiting the ubiquitin isopeptidases.

  • PR-619

    PR-619 is a non-selective, reversible inhibitor of the deubiquitinylating enzymes (DUBs) with EC50 of 1-20 μM in a cell-free assay.

  • USP8-IN-3

    USP8-IN-3 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with IC50 of 4.0 μM against USP8D.