AMPK-Activator-13

CAS No. 1243184-62-4

AMPK-Activator-13( MDK 4624 | AMPKα1 activator C13 | C13, Compound 13. )

Catalog No. M10984 CAS No. 1243184-62-4

A potent, allosteric, α1-selective small molecule activator of AMPK (EC50=20 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
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Biological Information

  • Product Name
    AMPK-Activator-13
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, allosteric, α1-selective small molecule activator of AMPK (EC50=20 nM).
  • Description
    A potent, allosteric, α1-selective small molecule activator of AMPK (EC50=20 nM); inhibits de novo lipogenesis in cellular and animal models of hyperlipidemia; the cell-permeable prodrug of compound 2 (AMPK-Activator-2).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MDK 4624 | AMPKα1 activator C13 | C13, Compound 13.
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    AMPK
  • Recptor
    AMPK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1243184-62-4
  • Formula Weight
    431.334
  • Molecular Formula
    C17H22NO10P
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)C(OCOP(C1=CC=C(C(C2)=NOC2=O)O1)(OCOC(C(C)C)=O)=O)=O
  • Chemical Name
    (((5-(5-oxo-4,5-dihydroisoxazol-3-yl)furan-2-yl)phosphoryl)bis(oxy))bis(methylene) bis(2-methylpropanoate)

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hunter RW, et al. Chem Biol. 2014 Jul 17;21(7):866-79. 2. Gómez-Galeno JE, et al. ACS Med Chem Lett. 2010 Aug 30;1(9):478-82.
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