Cart
sales@molnova.com
PI3Kα-IN-243
CAS No. 1235449-52-1
PI3Kα-IN-243( PI3Kα inhibitor 1 | MDK 9521 | PI3Kα-IN-243 )
Catalog No. M10945 CAS No. 1235449-52-1
A potent PI3Kα inhibitor with IC50 of <0.1 uM; also inhibits HDAC (IC50=0.1-1 uM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 158 | Get Quote |
|
| 5MG | 237 | Get Quote |
|
| 10MG | 357 | Get Quote |
|
| 25MG | 597 | Get Quote |
|
| 50MG | 851 | Get Quote |
|
| 100MG | 1152 | Get Quote |
|
| 500MG | 2313 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
| 1 mL x 10 mM in DMSO | 262 | In Stock |
|
| 5MG | 235 | In Stock |
|
| 10MG | 353 | In Stock |
|
| 25MG | 594 | In Stock |
|
| 50MG | 830 | In Stock |
|
| 100MG | 1097 | In Stock |
|
| 200MG | 1507 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NamePI3Kα-IN-243
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent PI3Kα inhibitor with IC50 of <0.1 uM; also inhibits HDAC (IC50=0.1-1 uM).
-
DescriptionA potent PI3Kα inhibitor with IC50 of <0.1 uM; also inhibits HDAC (IC50=0.1-1 uM); compound 243 in patent US/20120088764A1.
-
In Vitro——
-
In Vivo——
-
SynonymsPI3Kα inhibitor 1 | MDK 9521 | PI3Kα-IN-243
-
PathwayPI3K/Akt/mTOR signaling
-
TargetPI3K
-
RecptorPI3K
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1235449-52-1
-
Formula Weight507.5681
-
Molecular FormulaC23H25N9O3S
-
Purity>98% (HPLC)
-
SolubilityDMSO: ≥ 37 mg/mL
-
SMILESO=C(C1=CN=C(N(C)CC2=CC3=NC(C4=CC=C(NC)N=C4)=NC(N5CCOCC5)=C3S2)N=C1)NO
-
Chemical Name5-Pyrimidinecarboxamide, N-hydroxy-2-[methyl[[2-[6-(methylamino)-3-pyridinyl]-4-(4-morpholinyl)thieno[3,2-d]pyrimidin-6-yl]methyl]amino]-
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Patent US/20120088764A1
molnova catalog
related products
-
AS-605240
AS-605240 (AS605240) is a potent, selective, ATP-competitive, orally active PI3Kγ inhibitor.
-
PKI-402
A potent dual PI3K/mTOR inhibitor.
-
PI3Kα-IN-5
PI3Kα-IN-5 is a potent, selective PI3Kα inhibitor with enzyme IC50 and cell IC50 of 6 nM and 87 nM respectively.
