AZ20
CAS No. 1233339-22-4
AZ20( AZ20 | AZ-20 | AZ 20 )
Catalog No. M10924 CAS No. 1233339-22-4
AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM in a cell-free assay, 8-fold selectivity over mTOR.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 30 | In Stock |
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| 5MG | 47 | In Stock |
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| 10MG | 71 | In Stock |
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| 25MG | 131 | In Stock |
|
| 50MG | 235 | In Stock |
|
| 100MG | 348 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAZ20
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NoteResearch use only, not for human use.
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Brief DescriptionAZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM in a cell-free assay, 8-fold selectivity over mTOR.
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DescriptionAZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM in a cell-free assay, 8-fold selectivity over mTOR.
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In Vitro——
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In Vivo——
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SynonymsAZ20 | AZ-20 | AZ 20
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PathwayCell Cycle/DNA Damage
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TargetATM/ATR
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RecptorATR| mTOR
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1233339-22-4
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Formula Weight412.51
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Molecular FormulaC21H24N4O3S
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Purity>98% (HPLC)
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SolubilityEthanol: 3 mg/mL (7.27 mM); DMSO: 83 mg/mL (201.2 mM)
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SMILESC[C@H]1N(C2=NC(C3=CC=CC4=C3C=CN4)=NC(C5(S(=O)(C)=O)CC5)=C2)CCOC1
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Chemical Name(R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Xavier Jacq, et al. Y Res 2012;72(8 Suppl):Abstract nr 1823.
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