AZ20

CAS No. 1233339-22-4

AZ20( AZ20 | AZ-20 | AZ 20 )

Catalog No. M10924 CAS No. 1233339-22-4

AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM in a cell-free assay, 8-fold selectivity over mTOR.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 30 In Stock
5MG 47 In Stock
10MG 71 In Stock
25MG 131 In Stock
50MG 235 In Stock
100MG 348 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    AZ20
  • Note
    Research use only, not for human use.
  • Brief Description
    AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM in a cell-free assay, 8-fold selectivity over mTOR.
  • Description
    AZ20 is a novel potent and selective inhibitor of ATR kinase with IC50 of 5 nM in a cell-free assay, 8-fold selectivity over mTOR.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    AZ20 | AZ-20 | AZ 20
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    ATM/ATR
  • Recptor
    ATR| mTOR
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    1233339-22-4
  • Formula Weight
    412.51
  • Molecular Formula
    C21H24N4O3S
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 3 mg/mL (7.27 mM); DMSO: 83 mg/mL (201.2 mM)
  • SMILES
    C[C@H]1N(C2=NC(C3=CC=CC4=C3C=CN4)=NC(C5(S(=O)(C)=O)CC5)=C2)CCOC1
  • Chemical Name
    (R)-4-(2-(1H-indol-4-yl)-6-(1-(methylsulfonyl)cyclopropyl)pyrimidin-4-yl)-3-methylmorpholine

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Xavier Jacq, et al. Y Res 2012;72(8 Suppl):Abstract nr 1823.
molnova catalog
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