Cart
sales@molnova.com
VE822
CAS No. 1232416-25-9
VE822( VX-970 )
Catalog No. M10919 CAS No. 1232416-25-9
VE-822 is an ATR inhibitor with IC50 of 19 nM in HT29 cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 63 | In Stock |
|
| 10MG | 90 | In Stock |
|
| 25MG | 205 | In Stock |
|
| 50MG | 309 | In Stock |
|
| 100MG | 484 | In Stock |
|
| 200MG | 599 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVE822
-
NoteResearch use only, not for human use.
-
Brief DescriptionVE-822 is an ATR inhibitor with IC50 of 19 nM in HT29 cells.
-
DescriptionVE-822 is an ATR inhibitor with IC50 of 19 nM in HT29 cells.
-
In Vitro——
-
In Vivo——
-
SynonymsVX-970
-
PathwayCell Cycle/DNA Damage
-
TargetATM/ATR
-
RecptorATM| ATR
-
Research AreaCancer
-
Indication——
Chemical Information
-
CAS Number1232416-25-9
-
Formula Weight463.55
-
Molecular FormulaC24H25N5O3S
-
Purity>98% (HPLC)
-
SolubilityDMSO: 36 mg/mL (77.66 mM)
-
SMILESNC1=NC=C(C2=CC=C(S(=O)(C(C)C)=O)C=C2)N=C1C3=CC(C4=CC=C(CNC)C=C4)=NO3
-
Chemical Name5-(4-(isopropylsulfonyl)phenyl)-3-(3-(4-((methylamino)methyl)phenyl)isoxazol-5-yl)pyrazin-2-amine.
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1..Fokas E, et al. Cell Death Dis, 2012, 3, e44
molnova catalog
related products
-
GJ103 sodium salt
A novel small molecular read-through (SMRT) compound that can induce read through of nonsense mutations in the ATM gene.
-
Ro 90-7501
Ro 90-7501 is an amyloid β42 (Aβ42) protofibrillar and TPR-dependent PP5 inhibitor, a novel radiosensitizer for cervical cancer cells, which inhibits ATM phosphorylation, promotes apoptosis, and induces cell-cycle arrest.
-
CGK 733
CGK 733 is a potent and selective inhibitor of ATM/ATR with IC50 of ~200 nM.
