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Mps1-IN-2
CAS No. 1228817-38-6
Mps1-IN-2( —— )
Catalog No. M10891 CAS No. 1228817-38-6
Mps1-IN-2 is a potent Mps1 kianse inhibitor with IC50 value of 145 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 68 | In Stock |
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| 10MG | 93 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameMps1-IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionMps1-IN-2 is a potent Mps1 kianse inhibitor with IC50 value of 145 nM.
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DescriptionMps1-IN-2 is a potent Mps1 kianse inhibitor with IC50 value of 145 nM.
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In VitroMps1-IN-2 is a potent, selective and ATP-competitive Mps1 kinase inhibitor, with an IC50 and a Kd of 145 nM and 12 nM. Mps1-IN-2 also shows high affinity for PLK1 and GAK with Kds of 61 and 140 nM, respectively, but shows little or no inhibition on other 352 member kinases. Mps1-IN-2 can induces bypass of a checkpoint-mediated mitotic arrest in U2OS cells.
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In Vivo——
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Synonyms——
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetKinesin
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RecptorMps1
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1228817-38-6
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Formula Weight480.6
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Molecular FormulaC26H36N6O3
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESCCOC1=C(NC2=NC=C3N(C)C(=O)CCN(C4CCCC4)C3=N2)C=CC(=C1)N1CCC(O)CC1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Kwiatkowski N, et al. Nat Chem Biol. 2010 May;6(5):359-68.
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