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Rigosertib sodium (b)
CAS No. 1225497-78-8
Rigosertib sodium (b)( ON-01910 )
Catalog No. M10864 CAS No. 1225497-78-8
Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 68 | In Stock |
|
| 2MG | 32 | In Stock |
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| 5MG | 52 | In Stock |
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| 10MG | 92 | In Stock |
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| 25MG | 183 | In Stock |
|
| 50MG | 338 | In Stock |
|
| 100MG | 578 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRigosertib sodium (b)
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NoteResearch use only, not for human use.
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Brief DescriptionRigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM.
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DescriptionRigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3. Phase 3.
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In Vitro——
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In Vivo——
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SynonymsON-01910
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PathwayCell Cycle/DNA Damage
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TargetPLK
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RecptorPLK1
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number1225497-78-8
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Formula Weight473.47
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Molecular FormulaC21H24NNaO8S
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Purity>98% (HPLC)
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SolubilityWater: 95 mg/mL (200.64 mM); DMSO: 95 mg/mL (200.64 mM)
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SMILESCOC1=C(C=C(C=C1)CS(=O)(=O)/C=C/C2=C(C=C(C=C2OC)OC)OC)NCC(=O)[O-].[Na+]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Gumireddy K, et al. Y Cell, 2005, 7(3), 275-286.
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