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Chalcone 4 hydrate
CAS No. 1202866-96-3
Chalcone 4 hydrate( —— )
Catalog No. M10740 CAS No. 1202866-96-3
Chalcone 4 hydrate is a potent, selective inhibitor of CXCL12 binding to CXCR4 and CXCR7 with IC50 of 200 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 161 | In Stock |
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| 5MG | 256 | In Stock |
|
| 10MG | 344 | In Stock |
|
| 25MG | 562 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameChalcone 4 hydrate
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NoteResearch use only, not for human use.
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Brief DescriptionChalcone 4 hydrate is a potent, selective inhibitor of CXCL12 binding to CXCR4 and CXCR7 with IC50 of 200 nM.
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DescriptionChalcone 4 hydrate is a potent, selective inhibitor of CXCL12 binding to CXCR4 and CXCR7 with IC50 of 200 nM; shows no activities for CCL5 and CXCL8 chemokines; inhibits calcium responses mediated by CXCR4 and prevents CXCR4 internalization; blocks chemotaxis of human peripheral blood lymphocytes ex vivo, shows activity in vivo in mouse model of allergic eosinophilic airway inflammation.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayGPCR/G Protein
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TargetChemokine Receptor
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RecptorChemokine Receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number1202866-96-3
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Formula Weight306.74
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Molecular FormulaC16H15ClO4
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=CC=C(Cl)C=C1)/C=C/C2=CC=C(O)C(OC)=C2.O.[F,Cl,Br,I]
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Chemical Name(E)-1-(4-Chlorophenyl)-3-(4-hydroxy-3-methoxyphenyl)-2-propen-1-one hydrate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gasparik V, et al. ACS Med Chem Lett. 2011 Dec 9;3(1):10-4.
2. Hachet-Haas M, et al. J Biol Chem. 2008 Aug 22;283(34):23189-99.
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