Cart
sales@molnova.com
UR-144
CAS No. 1199943-44-6
UR-144( UR 144 | UR144 )
Catalog No. M10716 CAS No. 1199943-44-6
A potent, selective full agonist of the peripheral cannabinoid receptor CB2 with Ki of 1.8 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameUR-144
-
NoteResearch use only, not for human use.
-
Brief DescriptionA potent, selective full agonist of the peripheral cannabinoid receptor CB2 with Ki of 1.8 nM.
-
DescriptionA potent, selective full agonist of the peripheral cannabinoid receptor CB2 with Ki of 1.8 nM, >80-fold selectivity over CB2 (Ki=150 nM); possesses an EC50 of 421 nM for human CB1 receptors, and 72 nM for human CB2 receptors, produces bradycardia and hypothermia in rats at a dose of 10 mg/kg.
-
In Vitro——
-
In Vivo——
-
SynonymsUR 144 | UR144
-
PathwayGPCR/G Protein
-
TargetCannabinoid Receptor
-
RecptorCannabinoid Receptor
-
Research AreaNeurological Disease
-
Indication——
Chemical Information
-
CAS Number1199943-44-6
-
Formula Weight311.461
-
Molecular FormulaC21H29NO
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESCCCCCn1cc(c2c1cccc2)C(=O)C3C(C3(C)C)(C)C
-
Chemical Name(1-Pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Banister SD, et al. ACS Chem Neurosci. 2015 Aug 19;6(8):1445-58.
2. Dhopeshwarkar A, et al. J Pharmacol Exp Ther. 2016 Aug;358(2):342-51.
molnova catalog
related products
-
SCH-336
SCH-336 is a CB2 receptor agonist (Ki-1.8 nM, EC50-2 nM) with effective, selective, and oral activity. SCH-336 is also bioactive against CB1 receptor, and is 100 times more selective to CB2 receptor than CB1.
-
COR659
COR659 is a 2-acylaminothiophene derivative able to suppress alcohol and chocolate self-administration in rats, likely via positive allosteric modulation of the GABAB receptor and antagonism/inverse agonism at the cannabinoid CB1 receptor.
-
CB2 receptor agonist...
CB2 receptor agonist 2 is a potent and selective agonist for the CB2 (cannabinoid type 2) receptor, Ki = 8.5 nM. CB2 receptor agonist 2 has high affinity and selectivity for CB2.
