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CZC-54252
CAS No. 1191911-27-9
CZC-54252( CZC-54252 | CZC 54252 | CZC54252 )
Catalog No. M10659 CAS No. 1191911-27-9
CZC-54252 is a potent inhibitor of LRRK2 with IC50s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2 respectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 77 | In Stock |
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| 2MG | 43 | In Stock |
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| 5MG | 69 | In Stock |
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| 10MG | 112 | In Stock |
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| 25MG | 217 | In Stock |
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| 50MG | 322 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCZC-54252
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NoteResearch use only, not for human use.
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Brief DescriptionCZC-54252 is a potent inhibitor of LRRK2 with IC50s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2 respectively.
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DescriptionCZC-54252 is a potent inhibitor of LRRK2 with IC50s of 1.28 nM and 1.85 nM for wild-type and G2019S LRRK2 respectively.
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In Vitro——
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In Vivo——
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SynonymsCZC-54252 | CZC 54252 | CZC54252
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PathwayAutophagy
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TargetLRRK2
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RecptorLRRK2
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Research AreaNeurological Disease
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Indication——
Chemical Information
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CAS Number1191911-27-9
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Formula Weight504.39
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Molecular FormulaC22H25ClN6O4S
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Purity>98% (HPLC)
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SolubilityDMSO: 100 mM
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SMILESCS(=O)(NC1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCOCC4)C=C3OC)=NC=C2Cl)=O
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Chemical NameN-(2-((5-chloro-2-((2-methoxy-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)phenyl)methanesulfonamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Liu F, et al. J Pharmacol Exp Ther, 2008, 327(3), 827-839.
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