EB-42486

CAS No. 2390475-81-5

EB-42486( —— )

Catalog No. M28245 CAS No. 2390475-81-5

EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 164 In Stock
2MG 89 In Stock
5MG 150 In Stock
10MG 226 In Stock
25MG 409 In Stock
50MG 597 In Stock
100MG 848 In Stock
200MG 1135 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    EB-42486
  • Note
    Research use only, not for human use.
  • Brief Description
    EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.
  • Description
    EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 < 0.2 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    LRRK2
  • Recptor
    Human Endogenous Metabolite|VD2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2390475-81-5
  • Formula Weight
    414.46
  • Molecular Formula
    C22H22N8O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (301.60 mM)
  • SMILES
    CC1(C)n2nnnc2N(C)C(C)=C1C(Nc(cc1)cc2c1[nH]nc2-c1ccccc1)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Li L, et al. Performance evaluation of two immunoassays for 25-hydroxyvitamin D. J Clin Biochem Nutr. 2016 May;58(3):186-92.
molnova catalog
related products
  • GNE-7915

    A highly potent, selective, and brain-penetrant?LRRK2 inhibitor with IC50 of 1.9 nM.

  • GSK2578215A

    GSK2578215A is a highly potent, selective, BBB-permeable LRRK2 inhibitor with IC50 of 10.9 and 9.9 nM for wild-type LRRK2 and the G2019S mutant, respectively.

  • JH-II-127

    A potent and selective inhibitor of both wild-type and G2019S mutant LRRK2 with IC50 of 6.6 and 2.2 nM, respectively.