Cart
sales@molnova.com
Home - Products - GPCR/G Protein - Antibacterial - Relebactam

Relebactam

CAS No. 1174018-99-5

Relebactam( MK-7655 )

Catalog No. M10588 CAS No. 1174018-99-5

Relebactam (MK-7655) is a novel β-lactamase inhibitor that inhibited both class A and C β-lactamases in vitro.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 70 In Stock
5MG 83 In Stock
10MG 133 In Stock
25MG 248 In Stock
50MG 431 In Stock
100MG 646 In Stock
200MG 872 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Relebactam
  • Note
    Research use only, not for human use.
  • Brief Description
    Relebactam (MK-7655) is a novel β-lactamase inhibitor that inhibited both class A and C β-lactamases in vitro.
  • Description
    Relebactam (MK-7655) is a novel β-lactamase inhibitor that inhibited both class A and C β-lactamases in vitro; effectively restored imipenem's activity against imipenem-resistant Pseudomonas and Klebsiella strains at clinically achievable concentrations; reduces imipenem MICs for Enterobacteriaceae with KPC carbapenemases from 16-64 mg/L to 0.12-1 mg/L at a concentration of 4 mg/L.Bacterial Infection Phase 3 Clinical(In Vitro):Relebactam combine with Imipenem demonstrates activity against KPC-producing Enterobacteriaceae and multidrug-resistant P. aeruginosa.Relebactam shows limited inhibition of Class D-producing bacteria and has antipseudomonal activity.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    MK-7655
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    diazabicyclooctane
  • Research Area
    Infection
  • Indication
    Bacterial Infection

Chemical Information

  • CAS Number
    1174018-99-5
  • Formula Weight
    348.3754
  • Molecular Formula
    C12H20N4O6S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=S(O)(ON1[C@]2([H])CC[C@@H](C(NC3CCNCC3)=O)[N@@](C2)C1=O)=O
  • Chemical Name
    Sulfuric acid, mono[(1R,2S,5R)-7-oxo-2-[(4-piperidinylamino)carbonyl]-1,6-diazabicyclo[3.2.1]oct-6-yl] ester

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hirsch EB, et al. Antimicrob Agents Chemother. 2012 Jul;56(7):3753-7. 2. Blizzard TA, et al. Bioorg Med Chem Lett. 2014 Feb 1;24(3):780-5. 3. Livermore DM, et al. J Antimicrob Chemother. 2013 Oct;68(10):2286-90.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Macranthoside B

    Macranthoside B Iis a natural product?isolated from Flos Lonicerae possesses anti-bacterial activity.

  • 3-Hydroxy-C4-HSL

    3-Hydroxy-C4-HSL (N-3-hydroxybutyryl-L-Homoserine lactone) is an N-acyl homoserine lactone obtained from pathogenic Vibrio vulnificus in fish and is a bacterial group sensing (QS) inducer that modulates bacterial signaling and can be used in the study of bacterial infections.

  • PBP 10

    Selective formyl peptide receptor 2 (FPR2) antagonist; cell permeable. Selectively inhibits FPR2-mediated NADPH oxidase activity but has no effect on FPR1 signaling in neutrophils. Displays PIP2 binding activity in vitro and blocks cell motility. Also exhibits antiviral activity against influenza viruses via inhibition of viral-induced ERK activation.

Sign In Join Free