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GSK3β-IN-1a
CAS No. 1139875-74-3
GSK3β-IN-1a( —— )
Catalog No. M10492 CAS No. 1139875-74-3
GSK3β-IN-1a is a relatively selective and potent GSK-3β inhibitor with IC50 of 64 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 211 | Get Quote |
|
| 10MG | 374 | Get Quote |
|
| 25MG | 806 | Get Quote |
|
| 50MG | 1234 | Get Quote |
|
| 100MG | 1737 | Get Quote |
|
| 500MG | 3821 | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameGSK3β-IN-1a
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NoteResearch use only, not for human use.
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Brief DescriptionGSK3β-IN-1a is a relatively selective and potent GSK-3β inhibitor with IC50 of 64 nM.
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DescriptionGSK3β-IN-1a is a relatively selective and potent GSK-3β inhibitor with IC50 of 64 nM; induces replication of growth-arrested R7T1 β cells in a dose-dependent manner with EC50 of 1.1 uM, likely mediates β-cell proliferation through the Wnt signaling pathway.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayPI3K/Akt/mTOR signaling
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TargetGSK-3
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RecptorGSK-3
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Research Area——
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Indication——
Chemical Information
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CAS Number1139875-74-3
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Formula Weight413.924
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Molecular FormulaC20H20ClN5OS
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Purity>98% (HPLC)
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Solubility——
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SMILESCN1CCN(CC1)C(=O)C2=C(C=C(C=C2)NC3=NC=CC(=N3)C4=CC=CS4)Cl
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Chemical Name(2-chloro-4-((4-(thiophen-2-yl)pyrimidin-2-yl)amino)phenyl)(4-methylpiperazin-1-yl)methanone
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Wang W, et al. Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1427-32.
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