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LB-205
CAS No. 1113025-86-7
LB-205( LB 205 | LB205 )
Catalog No. M10416 CAS No. 1113025-86-7
A Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 873 | Get Quote |
|
| 50MG | 1782 | Get Quote |
|
| 100MG | 2250 | Get Quote |
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| 200MG | Get Quote | Get Quote |
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| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameLB-205
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NoteResearch use only, not for human use.
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Brief DescriptionA Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo.
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DescriptionA Zn2+-dependent pan-inhibitor of class I and class II HDACs with a long half-life (12h) in vivo; significantly enhances the migration of astrocytes and accelerates wound repair more effectively than SAHA and VPA; up-regulates the expression of NGF, phospho-TrkA, p-AKT, NF-κB, and Bcl-2, while down-regulates the expression of p75 NTR, phospho-JNK, and Bax.
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In Vitro——
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In Vivo——
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SynonymsLB 205 | LB205
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PathwayCell Cycle/DNA Damage
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TargetHDAC
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RecptorHDAC
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Research Area——
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Indication——
Chemical Information
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CAS Number1113025-86-7
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Formula Weight343.445
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Molecular FormulaC18H21N3O2S
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(NCCCCCC(NC1=CC=CC=C1)=O)C2=CC=CC=C2S
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Chemical Name2-mercapto-N-(6-oxo-6-(pyridin-3-ylamino)hexyl)benzamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lu J, et al. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21200-5.
2. Lu J, et al. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10747-52.
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