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Efonidipine hydrochloride monoethanolate
CAS No. 111011-76-8
Efonidipine hydrochloride monoethanolate( NZ-105 hydrochloride monoethanolate )
Catalog No. M10410 CAS No. 111011-76-8
Efonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 45 | Get Quote |
|
| 10MG | 73 | Get Quote |
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| 25MG | 157 | Get Quote |
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| 50MG | 284 | Get Quote |
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| 100MG | 368 | Get Quote |
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| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
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| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameEfonidipine hydrochloride monoethanolate
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NoteResearch use only, not for human use.
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Brief DescriptionEfonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker.
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DescriptionEfonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker, exhibits antihypertensive effect through vasodilatation; increases coronary blood flow by blocking L & T-type calcium channels and attenuates myocardial ischaemia, lowers blood pressure in cerebral resistance vessels and prevents hypertension induced brain damage; increases glomerular filtration rate without increasing intra-glomerular pressure and filtration fraction.
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In Vitro——
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In Vivo——
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SynonymsNZ-105 hydrochloride monoethanolate
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number111011-76-8
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Formula Weight714.1846
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Molecular FormulaC36H45ClN3O8P
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Purity>98% (HPLC)
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SolubilityDMSO: 8.5 mg/mL
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SMILESCCO.CC1=C(C(C(=C(N1)C)P2(=O)OCC(CO2)(C)C)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5.Cl
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Chemical Name3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, hydrochloride, compd. with 2-[phenyl(phenylmethyl)amino]ethyl 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Masuda Y, et al. Arch Int Pharmacodyn Ther. 1990 Mar-Apr;304:247-64.
2. Tamura T, et al. Naunyn Schmiedebergs Arch Pharmacol. 1991 Apr;343(4):405-10.
3. Shudo C, et al. Gen Pharmacol. 1994 Nov;25(7):1451-8.
4. Yamashita T, et al. Jpn J Pharmacol. 1991 Nov;57(3):337-48.
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