Cart
sales@molnova.com
Efonidipine
CAS No. 111011-63-3
Efonidipine( NZ-105 | (±)-Efonidipine )
Catalog No. M10409 CAS No. 111011-63-3
Efonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 48 | In Stock |
|
| 5MG | 33 | In Stock |
|
| 10MG | 55 | In Stock |
|
| 25MG | 106 | In Stock |
|
| 50MG | 166 | In Stock |
|
| 100MG | 269 | In Stock |
|
| 200MG | 403 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameEfonidipine
-
NoteResearch use only, not for human use.
-
Brief DescriptionEfonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker.
-
DescriptionEfonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker, exhibits antihypertensive effect through vasodilatation; increases coronary blood flow by blocking L & T-type calcium channels and attenuates myocardial ischaemia, lowers blood pressure in cerebral resistance vessels and prevents hypertension induced brain damage; increases glomerular filtration rate without increasing intra-glomerular pressure and filtration fraction.
-
In Vitro——
-
In Vivo——
-
SynonymsNZ-105 | (±)-Efonidipine
-
PathwayGPCR/G Protein
-
TargetCalcium Channel
-
RecptorCalciumChannel
-
Research AreaCardiovascular Disease
-
Indication——
Chemical Information
-
CAS Number111011-63-3
-
Formula Weight631.6552
-
Molecular FormulaC34H38N3O7P
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESO=C(C1=C(C)NC(C)=C(P2(OCC(C)(C)CO2)=O)C1C3=CC=CC([N+]([O-])=O)=C3)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5
-
Chemical Name3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[phenyl(phenylmethyl)amino]ethyl ester
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Masuda Y, et al. Arch Int Pharmacodyn Ther. 1990 Mar-Apr;304:247-64.
2. Tamura T, et al. Naunyn Schmiedebergs Arch Pharmacol. 1991 Apr;343(4):405-10.
3. Shudo C, et al. Gen Pharmacol. 1994 Nov;25(7):1451-8.
4. Yamashita T, et al. Jpn J Pharmacol. 1991 Nov;57(3):337-48.
molnova catalog
related products
-
Ethyl cinnamate
Ethyl cinnamate has antifungal, and vasorelaxant effects. Ethyl cinnamate can lead to the damage of cell membrane system and metabolic disorder through inducing lipid peroxidation via initiating ROS overproduction.
-
GV-58
GV-58 is a potent, selective N-Type and P/Q-type Ca2+ Channel agonist with EC50 of 7.2 and 8.8 uM.
-
Flunarizine dihydroc...
Flunarizine is a selective calcium entry blocker.
