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Efonidipine hydrochloride
CAS No. 111011-53-1
Efonidipine hydrochloride( NZ-105 hydrochloride )
Catalog No. M10408 CAS No. 111011-53-1
Efonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1413 | Get Quote |
|
| 50MG | 2862 | Get Quote |
|
| 100MG | 3870 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameEfonidipine hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionEfonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker.
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DescriptionEfonidipine (NZ-105) is a potent, dual T-type and L-type calcium channel blocker, exhibits antihypertensive effect through vasodilatation; increases coronary blood flow by blocking L & T-type calcium channels and attenuates myocardial ischaemia, lowers blood pressure in cerebral resistance vessels and prevents hypertension induced brain damage; increases glomerular filtration rate without increasing intra-glomerular pressure and filtration fraction.
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In Vitro——
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In Vivo——
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SynonymsNZ-105 hydrochloride
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number111011-53-1
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Formula Weight668.1161
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Molecular FormulaC34H39ClN3O7P
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Purity>98% (HPLC)
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SolubilityDMSO: 8.5 mg/mL
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SMILESCC1=C(C(C(=C(N1)C)P2(=O)OCC(CO2)(C)C)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCN(CC4=CC=CC=C4)C5=CC=CC=C5.Cl
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Chemical Name3-Pyridinecarboxylic acid, 5-(5,5-dimethyl-2-oxido-1,3,2-dioxaphosphorinan-2-yl)-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[phenyl(phenylmethyl)amino]ethyl ester, hydrochloride (1:1)
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Masuda Y, et al. Arch Int Pharmacodyn Ther. 1990 Mar-Apr;304:247-64.
2. Tamura T, et al. Naunyn Schmiedebergs Arch Pharmacol. 1991 Apr;343(4):405-10.
3. Shudo C, et al. Gen Pharmacol. 1994 Nov;25(7):1451-8.
4. Yamashita T, et al. Jpn J Pharmacol. 1991 Nov;57(3):337-48.
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