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Home - Products - Wnt/Notch/Hedgehog - Beta-catenin - FH535

FH535

CAS No. 108409-83-2

FH535( FH 535 | FH-535 )

Catalog No. M10331 CAS No. 108409-83-2

A dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 55 In Stock
5MG 30 In Stock
10MG 49 In Stock
25MG 90 In Stock
50MG 155 In Stock
100MG 268 In Stock
200MG 395 In Stock
500MG 640 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    FH535
  • Note
    Research use only, not for human use.
  • Brief Description
    A dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment.
  • Description
    A dual PPARγ/δ antagonist that is able to inhibit GRIP1 and β-catenin recruitment; antagonizes β-catenin/Tcf–mediated transcription and inhibits the Wnt/β-catenin pathway; shows antiproliferation effect on transformed colon lung and liver cell lines.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    FH 535 | FH-535
  • Pathway
    Wnt/Notch/Hedgehog
  • Target
    Beta-catenin
  • Recptor
    PPARγ|PPARδ|Wnt/β-catenin
  • Research Area
    Cancer
  • Indication
    ——

Chemical Information

  • CAS Number
    108409-83-2
  • Formula Weight
    361.2005
  • Molecular Formula
    C13H10Cl2N2O4S
  • Purity
    >98% (HPLC)
  • Solubility
    10 mM in DMSO
  • SMILES
    O=S(C1=CC(Cl)=CC=C1Cl)(NC2=CC=C([N+]([O-])=O)C=C2C)=O
  • Chemical Name
    Benzenesulfonamide, 2,5-dichloro-N-(2-methyl-4-nitrophenyl)-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Handeli S, et al. Mol Cancer Ther. 2008 Mar;7(3):521-9. 2. Gedaly R, et al. PLoS One. 2014 Jun 18;9(6):e99272. 3. Su H, et al. J Transl Med. 2015 Mar 31;13:104.
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