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N-Acetyl-Calicheamicin
CAS No. 108212-76-6
N-Acetyl-Calicheamicin( N-Acetyl-Calicheamicin γ | N-Acetyl-γ-calicheamicin )
Catalog No. M10325 CAS No. 108212-76-6
N-Acetyl-Calicheamicin is a enediyne antitumor antibiotic; targets DNA and causes strand scission.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1169 | In Stock |
|
| 10MG | 1587 | In Stock |
|
| 25MG | 2356 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameN-Acetyl-Calicheamicin
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NoteResearch use only, not for human use.
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Brief DescriptionN-Acetyl-Calicheamicin is a enediyne antitumor antibiotic; targets DNA and causes strand scission.
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DescriptionN-Acetyl-Calicheamicin is a enediyne antitumor antibiotic; targets DNA and causes strand scission; a ADC payload in antibody drug conjugates development.
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In Vitro——
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In Vivo——
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SynonymsN-Acetyl-Calicheamicin γ | N-Acetyl-γ-calicheamicin
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research AreaCancer
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Indication——
Chemical Information
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CAS Number108212-76-6
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Formula Weight1410.385
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Molecular FormulaC57H76IN3O22S4
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCCN(C1COC(CC1OC)OC2C(C(C(OC2OC3C#CC=CC#CC4(CC(=O)C(=C3C4=CCSSSC)NC(=O)OC)O)C)NOC5CC(C(C(O5)C)SC(=O)C6=C(C(=C(C(=C6OC)OC)OC7C(C(C(C(O7)C)O)OC)O)I)C)O)O)C(=O)C
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Chemical NameCarbamic acid, [(1R,4Z,8S,13E)-8-[[2-O-[4-(acetylethylamino)-2,4-dideoxy-3-O-methyl-α-L-threo-pentopyranosyl]-4,6-dideoxy-4-[[[2,6-dideoxy-4-S-[4-[(6-deoxy-3-O-methyl-α-L-mannopyranosyl)oxy]-3-iodo-5,6-dimethoxy-2-methylbenzoyl]-4-thio-β-D-ribo-hexopyrano
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Stasi R, et al. Cancer Treat Rev. 2008 Feb;34(1):49-60.
2. Naito K, et al. Leukemia. 2000 Aug;14(8):1436-43.
3. Hills RK, et al. Lancet Oncol. 2014 Aug;15(9):986-96.
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