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ANY1

CAS No. 482574-02-7

ANY1( FosA inhibitor ANY1 )

Catalog No. M14617 CAS No. 482574-02-7

ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ANY1
  • Note
    Research use only, not for human use.
  • Brief Description
    ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA).
  • Description
    ANY1 (FosA inhibitor ANY1) is a small molecule active site inhibitor of FosA (metal-dependent glutathione S-transferase) with IC50 of 5.1 uM (K. pneumoniae FosA); binds to wild-type and mutant FosA3 measured by fluorescence quenching with Kd vales of 440-4880 nM; potentiates Fosfomycin (FOM) activity in representative Gram-negative pathogens.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    FosA inhibitor ANY1
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    482574-02-7
  • Formula Weight
    537.088
  • Molecular Formula
    C15H7Br2N9O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    3-bromo-6-[3-(3-bromo-2-oxo-1H-pyrazolo[1,5-a]pyrimidin-6-yl)-4-nitro-1H-pyrazol-5-yl]-1H-pyrazolo[1,5-a]pyrimidin-2-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tomich AD, et al. Antimicrob Agents Chemother. 2019 Jan 14. pii: AAC.01524-18.
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