Home - Products - Endocrinology/Hormones - 5-HT Receptor - PF-03246799

PF-03246799

CAS No. 1065110-62-4

PF-03246799( PF 03246799 | PF03246799 | PF-3246799 )

Catalog No. M10282 CAS No. 1065110-62-4

A potent and selective 5-HT2C receptor agonist with EC50 of 190 nM, with excellent selectivity for 5-HT2C over 5-HT2A.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	873	Get Quote
50MG	1782	Get Quote
100MG	2250	Get Quote
200MG	Get Quote	Get Quote
500MG	Get Quote	Get Quote
1G	Get Quote	Get Quote

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

PF-03246799
Note

Research use only, not for human use.
Brief Description

A potent and selective 5-HT2C receptor agonist with EC50 of 190 nM, with excellent selectivity for 5-HT2C over 5-HT2A.
Description

A potent and selective 5-HT2C receptor agonist with EC50 of 190 nM, with excellent selectivity for 5-HT2C over 5-HT2A; has minimal activation at either the 5-HT(2A) or 5-HT(2B) receptors, demonstrates robust efficacy in preclinical canine model of stress urinary incontinence (SUI) and attractive pharmacokinetic and safety properties.
In Vitro

——
In Vivo

——
Synonyms

PF 03246799 | PF03246799 | PF-3246799
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

1065110-62-4
Formula Weight

239.322
Molecular Formula

C15H17N3
Purity

>98% (HPLC)
Solubility

——
SMILES

C12=NC(CC3=CC=CC=C3)=NC=C1CCNCC2
Chemical Name

2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Andrews MD, et al. Bioorg Med Chem Lett. 2011 May 1;21(9):2715-20. 2. Dvorak CA, et al. ACS Med Chem Lett. 2015 Jul 20;6(9):1015-8.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Lerisetron

Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity.
Pergolide mesylate s...

PERGOLIDE MESYLATE is a long-acting dopamine agonist which has been used to treat parkinson disease and hyperprolactinemiabut withdrawn from some markets due to potential for heart valve diseases.
Cinitapride

Cinitapride is a gastroprokinetic agent. It slows the actions of the muscles to reduce the symptoms of conditions such as acid reflux, delayed gastric emptying, and ulcer dyspepsia.

Sign In Join Free