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Anlotinib
CAS No. 1058156-90-3
Anlotinib( AL-3818 )
Catalog No. M10263 CAS No. 1058156-90-3
Anlotinib (AL-3818) is a novel multi-target tyrosine kinase that primarily inhibit VEGFR2/3, FGFR1-4, PDGFR α/β, c-Kit, and Ret.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameAnlotinib
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NoteResearch use only, not for human use.
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Brief DescriptionAnlotinib (AL-3818) is a novel multi-target tyrosine kinase that primarily inhibit VEGFR2/3, FGFR1-4, PDGFR α/β, c-Kit, and Ret.
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DescriptionAnlotinib (AL-3818) is a novel multi-target tyrosine kinase that primarily inhibit VEGFR2/3, FGFR1-4, PDGFR α/β, c-Kit, and Ret; shows antitumor activity against tumor cells carrying mutations in PDGFR α, c-Kit, Met, and epidermal growth factor receptor (EGFR).Colon Cancer Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsAL-3818
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PathwayAngiogenesis
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TargetEGFR
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RecptorEGFR
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Research AreaCancer
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IndicationColon Cancer
Chemical Information
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CAS Number1058156-90-3
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Formula Weight407.4375
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Molecular FormulaC23H22FN3O3
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Purity>98% (HPLC)
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SolubilityDMSO: ≥ 44 mg/mL
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SMILESCC1=CC2=C(N1)C=CC(=C2F)OC3=C4C=C(C(=CC4=NC=C3)OCC5(CC5)N)OC
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Chemical NameCyclopropanamine, 1-[[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-quinolinyl]oxy]methyl]-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Sun Y, et al. J Hematol Oncol. 2016 Oct 4;9(1):105.
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