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Dexpramipexole
CAS No. 104632-28-2
Dexpramipexole( R)-Pramipexole | KNS-760704 )
Catalog No. M10230 CAS No. 104632-28-2
A partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 29 | In Stock |
|
| 5MG | 42 | In Stock |
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| 10MG | 69 | In Stock |
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| 25MG | 140 | In Stock |
|
| 50MG | 212 | In Stock |
|
| 100MG | 303 | In Stock |
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| 200MG | 452 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDexpramipexole
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NoteResearch use only, not for human use.
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Brief DescriptionA partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively.
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DescriptionA partial/full agonist of dopamine receptor with Ki of 3.9/2.2/0.5/5.1 nM for D2S/D2L/D3/D4, respeectively; also possesses low/insignificant affinity (500–10,000 nM) for the 5-HT1A, 5-HT1B, 5-HT1D, and α2-adrenergic receptors; used for treating Parkinson's disease (PD) and restless legs syndrome (RLS).Alzheimer's Disease Phase 2 Clinical.
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In Vitro——
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In Vivo——
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SynonymsR)-Pramipexole | KNS-760704
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PathwayGPCR/G Protein
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TargetDopamine Receptor
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RecptorDopamine Receptor
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Research AreaNeurological Disease
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IndicationAlzheimer Disease
Chemical Information
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CAS Number104632-28-2
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Formula Weight211.3271
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Molecular FormulaC10H17N3S
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Purity>98% (HPLC)
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Solubility10 mM in DMSO
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SMILESCCCNC1CCC2=C(C1)SC(=N2)N
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Chemical Name2,6-Benzothiazolediamine, 4,5,6,7-tetrahydro-N6-propyl-, (6R)-
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Alavian KN, et al. Brain Res. 2012 Mar 29;1446:1-11.
2. Cudkowicz M, et al. Nat Med. 2011 Nov 20;17(12):1652-6.
3. Bozik ME, et al. J Clin Pharmacol. 2011 Aug;51(8):1177-85.
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