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Levamlodipine
CAS No. 103129-82-4
Levamlodipine( Levamlodipine | S-Amlodipine | )
Catalog No. M10152 CAS No. 103129-82-4
Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 25MG | 36 | In Stock |
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| 50MG | 51 | In Stock |
|
| 100MG | 71 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | 176 | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameLevamlodipine
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NoteResearch use only, not for human use.
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Brief DescriptionAmlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.
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DescriptionAmlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug response (MDR) activity through inhibition of the p-glycoprotein efflux pump.
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In Vitro——
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In Vivo——
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SynonymsLevamlodipine | S-Amlodipine |
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PathwayGPCR/G Protein
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TargetCalcium Channel
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RecptorCalcium Channel
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Research Area——
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Indication——
Chemical Information
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CAS Number103129-82-4
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Formula Weight408.88
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Molecular FormulaC20H25N2O5Cl
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Purity>98% (HPLC)
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SolubilityDMSO: 10 mM
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SMILESO=C(C1=C(COCCN)NC(C)=C(C(OC)=O)[C@@H]1C2=CC=CC=C2Cl)OCC
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Chemical Name3-ethyl 5-methyl (S)-2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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Diltiazem
Diltiazem (CRD 401 free base) is an orally available L-type Ca2+ channel blocker with antihypertensive, antiarrhythmic, and cardioprotective properties that prevent post-reperfusion myocardial injury, angina pectoris, and cardiovascular-related diseases.
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Ticolubant
Ticolubant is orally active leukotriene B4 antagonist with high affinity for the human neutrophil LTB4 receptor (Ki = 0.78 nM), blocks LTB4-induced Ca2+ migration with an IC50 of 6.6 ± 1.5 nM, and shows topical anti-inflammatory activity in a mouse model of skin inflammation.
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N-Desalkylflurazepam
N-Desalkylflurazepam (Norfludiazepam) is a long-acting metabolite of benzodiazepine compounds, such as Flurazepam. N-Desalkylflurazepam inhibits L-type voltage-gated calcium channels with IC 50 values of 55 μM and 37 μM for Ca v 1.2 and Ca v 1.3 , respectively.
