Levamlodipine( Levamlodipine | S-Amlodipine | )

Catalog No. M10152 CAS No. 103129-82-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Levamlodipine
Note

Research use only, not for human use.
Brief Description

Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties.
Description

Amlodipine is a synthetic dihydropyridine and a calcium channel blocker with antihypertensive and antianginal properties. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. This results in a dilatation of the main coronary and systemic arteries, decreased myocardial contractility, increased blood flow and oxygen delivery to the myocardial tissue, and decreased total peripheral resistance. This agent may also modulate multi-drug response (MDR) activity through inhibition of the p-glycoprotein efflux pump.
In Vitro

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In Vivo

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Synonyms

Levamlodipine | S-Amlodipine |
Pathway

GPCR/G Protein
Target

Calcium Channel
Recptor

Calcium Channel
Research Area

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Indication

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CAS Number

103129-82-4
Formula Weight

408.88
Molecular Formula

C20H25N2O5Cl
Purity

>98% (HPLC)
Solubility

DMSO: 10 mM
SMILES

O=C(C1=C(COCCN)NC(C)=C(C(OC)=O)[C@@H]1C2=CC=CC=C2Cl)OCC
Chemical Name

3-ethyl 5-methyl (S)-2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

1.Gui H, et al. CNS Neurosci Ther. 2013 Mar;19(3):178-82.

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