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Levetiracetam

CAS No. 102767-28-2

Levetiracetam( UCB L059 )

Catalog No. M10134 CAS No. 102767-28-2

Levetiracetam(UCB L059) is a novel anticonvulsant with antihyperalgesic efficacy in inflammatory pain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 48 In Stock
10MG 29 In Stock
25MG 42 In Stock
50MG 54 In Stock
100MG 91 In Stock
200MG Get Quote In Stock
500MG 238 In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Levetiracetam
  • Note
    Research use only, not for human use.
  • Brief Description
    Levetiracetam(UCB L059) is a novel anticonvulsant with antihyperalgesic efficacy in inflammatory pain.
  • Description
    Levetiracetam(UCB L059) is a novel anticonvulsant with antihyperalgesic efficacy in inflammatory pain.(In Vitro):Levetiracetam increases the transcription of HDACs and recruits corepressor complex on O6-Methylguanine-DNA-methyltransferase (MGMT) promoter, thus silencing its activity.Levetiracetam sensitizes (40 μg/mL) glioblastoma multiforme stem-like cells (GSCs) to Temozolomide (250 μM) treatment.MGMT expression is downregulated in GCSCs treated with Levetiracetam (40 μg/mL)(In Vivo):Levetiracetam (10, 25, or 50 mg/kg) suppresses behavioral and electrographic seizure activity during neonatal hypoxia.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male Long-Evans ratsDosage:10, 25, or 50?mg/kg Administration:Intraperitoneal injection 60?min before hypoxia. Result:Treatment resulted in a significant decrease in hypoxic seizure (HS) duration at 25?mg/kg and at 50?mg/kg. Anti convulsant activity was maximal at 50?mg/kg, at which HSs were reduced by 63.6%.
  • Synonyms
    UCB L059
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    Calcium Channel| Synaptic vesicle glycoprotein 2A
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    102767-28-2
  • Formula Weight
    170.21
  • Molecular Formula
    C8H14N2O2
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol: 34 mg/mL (199.75 mM); Water: 34 mg/mL (199.75 mM); DMSO: 34 mg/mL (199.75 mM)
  • SMILES
    O=C(N)[C@H](CC)N1C(CCC1)=O
  • Chemical Name
    (S)-2-(2-oxopyrrolidin-1-yl)butanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Lynch BA, et al. Proc Natl Acad Sci U S A. 2004 Jun 29;101(26):9861-6.
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