BMS-741672( BMS741672 )

Catalog No. M10035 CAS No. 1004757-96-3

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

BMS-741672
Note

Research use only, not for human use.
Brief Description

BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.
Description

BMS-741672 is a potent, selective CCR2 antagonist for the treatment of neuropathic pain.Diabetes Phase 2 Clinical.
In Vitro

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In Vivo

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Synonyms

BMS741672
Pathway

GPCR/G Protein
Target

Chemokine Receptor
Recptor

Chemokine Receptor
Research Area

Metabolic Disease
Indication

Diabetes

CAS Number

1004757-96-3
Formula Weight

506.574
Molecular Formula

C25H33F3N6O2
Purity

>98% (HPLC)
Solubility

——
SMILES

CC(N[C@H]1[C@@H](N2C([C@@H](NC3=C4C=C(C(F)(F)F)C=CC4=NC=N3)CC2)=O)CC[C@@H](N(C(C)C)C)C1)=O
Chemical Name

N-((lR,2S,5R)-5-(isopropyl(methyl)amino)-2-((S)-2-oxo-3-(6- (trifluoromethyl)quinazolin-4-ylamino)pyrrolidin-l-yl)cyclohexyl)acetamide

1. Joerg Deerberg, et al. Org. Process Res. Dev., 2016, 20 (11), pp 1949-1966.

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