SRT1720

CAS No. 1001645-58-4

SRT1720( CAY10559 | SIRT 1933 )

Catalog No. M10020 CAS No. 1001645-58-4

SRT1720 hydrochloride is a selective activator of human SIRT1.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 221 In Stock
2MG 78 In Stock
5MG 135 In Stock
10MG 250 In Stock
25MG 394 In Stock
50MG 550 In Stock
100MG 784 In Stock
200MG 1079 In Stock
500MG 1600 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    SRT1720
  • Note
    Research use only, not for human use.
  • Brief Description
    SRT1720 hydrochloride is a selective activator of human SIRT1.
  • Description
    SRT1720 hydrochloride is a selective activator of human SIRT1 (EC1.5 = 0.16 μM) versus the closest sirtuin homologues, SIRT2 and SIRT3 (SIRT2: EC1.5 = 37 μM;SIRT3: EC1.5 > 300 μM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    CAY10559 | SIRT 1933
  • Pathway
    Chromatin/Epigenetic
  • Target
    Sirtuin
  • Recptor
    SIRT1
  • Research Area
    Metabolic Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    1001645-58-4
  • Formula Weight
    506.22
  • Molecular Formula
    C25H24ClN7OS
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 38 mg/mL (75.09 mM)
  • SMILES
    Cl.O=C(NC1=CC=CC=C1C1=CN2C(CN3CCNCC3)=CSC2=N1)C1=NC2=CC=CC=C2N=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Milne JC, et al. Nature. 2007, 450(7170), 712-716.
molnova catalog
related products
  • SirT1 enhancer A03

    SirT1 enhancer A03 is a specific, orally bioavailable, brain penetrant apolipoprotein E4 (ApoE4)-targeted sirtuin1 (SirT1) enhancer.

  • Ophiopogonin D (b)

    Ophiopogonin D' can activate SIRT1 in a dose-dependent manner. Ophiopogonin D' also noncompetitively inhibits UGT1A6 and UGT1A10.

  • Selisistat R-enantio...

    Selisistat R-enantiomer is a SIRT1 inhibitor with much less activity than the R-enantiomer of Selisistat (IC50 of SIRT1 > 100 μM).