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Lumiracoxib

CAS No. 220991-20-8

Lumiracoxib ( CGS-35189;CGS35189; COX 189; Lumiracoxib )

Catalog No. M18251 CAS No. 220991-20-8

Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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25MG 65 In Stock
50MG 87 In Stock
100MG 113 In Stock
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Biological Information

  • Product Name
    Lumiracoxib
  • Note
    Research use only, not for human use.
  • Brief Description
    Lumiracoxib is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.
  • Description
    Lumiracoxib, also known as CGS 35189 and COX 189, is a COX-2 selective inhibitor non-steroidal anti-inflammatory drug, manufactured by Novartis and still sold in few countries, including Mexico, Ecuador and the Dominican Republic, under the trade name Prexige. Since its original approval, lumiracoxib has been withdrawn from the market in several countries, mostly due to its potential for causing liver failure (sometimes requiring liver transplantation). It has never been approved for use in the United States.
  • Synonyms
    CGS-35189;CGS35189; COX 189; Lumiracoxib
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    COX-1; COX-2
  • Research Area
    Others-Field
  • Indication
    ——

Chemical Information

  • CAS Number
    220991-20-8
  • Formula Weight
    293.72
  • Molecular Formula
    C15H13ClFNO2
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    Clc2cccc(F)c2Nc1ccc(C)cc1CC(=O)O
  • Chemical Name
    2-(2-((2-chloro-6-fluorophenyl)amino)-5-methylphenyl)acetic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Esser R, et al. Br J Pharmacol, 2005, 144(4), 538-550.
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