Loxapine ( Adasuve; AZ-004; CL 62,362; Cloxazepine; Dibenzacepin; Dibenzoazepine; HF 3170; HF3170 )

Catalog No. M13090 CAS No. 1977-10-2

A typical antipsychotic agent that displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

Loxapine
Note

Research use only, not for human use.
Brief Description

A typical antipsychotic agent that displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors.
Description

A typical antipsychotic agent that displays an extremely strong binding affinity for dopamine D4 and serotonin 5-HT2 receptors.Schizophrenia Approved
Synonyms

Adasuve; AZ-004; CL 62,362; Cloxazepine; Dibenzacepin; Dibenzoazepine; HF 3170; HF3170
Pathway

Endocrinology/Hormones
Target

5-HT Receptor
Recptor

5-HT Receptor
Research Area

Neurological Disease
Indication

Schizophrenia

Chemical Information

CAS Number

1977-10-2
Formula Weight

327.81
Molecular Formula

C18H18ClN3O
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

CN1CCN(C2=NC3=CC=CC=C3OC4=CC=C(Cl)C=C24)CC1
Chemical Name

Dibenz[b,f][1,4]oxazepine, 2-chloro-11-(4-methyl-1-piperazinyl)-

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Singh AN, et al. J Psychiatry Neurosci. 1996 Jan;21(1):29-35.
2. Labuzek K, et al. Eur Neuropsychopharmacol. 2005 Jan;15(1):23-30.
3. Lee T, et al. Psychiatry Res. 1984 Aug;12(4):277-85.

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