Cart
sales@molnova.com
Loratadine
CAS No. 79794-75-5
Loratadine ( Loratidine;SCH-29851 )
Catalog No. M15987 CAS No. 79794-75-5
A tricyclic antihistamine that acts as a selective inverse agonist of peripheral histamine H1-receptors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 500MG | 37 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameLoratadine
-
NoteResearch use only, not for human use.
-
Brief DescriptionA tricyclic antihistamine that acts as a selective inverse agonist of peripheral histamine H1-receptors.
-
DescriptionA tricyclic antihistamine that acts as a selective inverse agonist of peripheral histamine H1-receptors.Allergy Approved
-
SynonymsLoratidine;SCH-29851
-
PathwayGPCR/G Protein
-
TargetHistamine Receptor
-
RecptorB(0)AT2
-
Research AreaInflammation/Immunology
-
IndicationAllergy
Chemical Information
-
CAS Number79794-75-5
-
Formula Weight382.88
-
Molecular FormulaC22H23ClN2O2
-
Purity>98% (HPLC)
-
Solubility10 mM in DMSO
-
SMILESCCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1
-
Chemical Name1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Devillier P, et al. Clin Pharmacokinet. 2008;47(4):217-30.
2. Barnett A, et al. Agents Actions. 1984 Jun;14(5-6):590-7.
3. Roman IJ, et al. Clin Rev Allergy. 1993 Spring;11(1):89-110.
2. Barnett A, et al. Agents Actions. 1984 Jun;14(5-6):590-7.
3. Roman IJ, et al. Clin Rev Allergy. 1993 Spring;11(1):89-110.
molnova catalog
related products
-
PF-03654746
PF-03654746 (PF 3654746) is a potent, selective, orally bioactive antagonist of H3 receptor with Ki of 2.3 nM.
-
Tanshinone IIA
Tanshinone IIA(Tanshinone B) is the diterpene quinone in Danshen, which is utilized in the treatment of cardiovascular and inflammatory.
-
Thioperamide maleate
Thioperamide maleate is an effective and selective antagonist of H3 receptor (Ki = 4.3 nM) for inhibition of [3H]histamine synthesis (Ki = 31 nM).
