Loratadine ( Loratidine;SCH-29851 )

Catalog No. M15987 CAS No. 79794-75-5

A tricyclic antihistamine that acts as a selective inverse agonist of peripheral histamine H1-receptors.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

Loratadine
Note

Research use only, not for human use.
Brief Description

A tricyclic antihistamine that acts as a selective inverse agonist of peripheral histamine H1-receptors.
Description

A tricyclic antihistamine that acts as a selective inverse agonist of peripheral histamine H1-receptors.Allergy Approved
Synonyms

Loratidine;SCH-29851
Pathway

GPCR/G Protein
Target

Histamine Receptor
Recptor

B(0)AT2
Research Area

Inflammation/Immunology
Indication

Allergy

Chemical Information

CAS Number

79794-75-5
Formula Weight

382.88
Molecular Formula

C22H23ClN2O2
Purity

>98% (HPLC)
Solubility

10 mM in DMSO
SMILES

CCOC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1
Chemical Name

1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Devillier P, et al. Clin Pharmacokinet. 2008;47(4):217-30.
2. Barnett A, et al. Agents Actions. 1984 Jun;14(5-6):590-7.
3. Roman IJ, et al. Clin Rev Allergy. 1993 Spring;11(1):89-110.

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