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Lofepramine
CAS No. 23047-25-8
Lofepramine( Lopramine | Amplit | Leo 640 | Gamanil )
Catalog No. M26742 CAS No. 23047-25-8
Lofepramine is a potent tricyclic antidepressant that is extensively metabolized to desipramine.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 37 | Get Quote |
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| 5MG | 59 | Get Quote |
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| 10MG | 82 | Get Quote |
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| 25MG | 169 | Get Quote |
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| 50MG | 253 | Get Quote |
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| 100MG | 380 | Get Quote |
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| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameLofepramine
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NoteResearch use only, not for human use.
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Brief DescriptionLofepramine is a potent tricyclic antidepressant that is extensively metabolized to desipramine.
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DescriptionLofepramine is a potent tricyclic antidepressant that is extensively metabolized to desipramine. It inhibits the serotonin and norepinephrine transporters by inhibiting neurons with Kd values of 70 and 5.4 nM, respectively, with weak antagonism of serotonin, histamine and muscarinic receptors.
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In Vitro——
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In Vivo——
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SynonymsLopramine | Amplit | Leo 640 | Gamanil
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PathwayEndocrinology/Hormones
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Target5-HT Receptor
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RecptorTopo II
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Research Area——
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Indication——
Chemical Information
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CAS Number23047-25-8
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Formula Weight418.97
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Molecular FormulaC26H27ClN2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (119.34 mM)
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SMILESCN(CCCN1c2ccccc2CCc2ccccc12)CC(=O)c1ccc(Cl)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.J P Braybrooke, et al. A phase II study of Razoxane, an antiangiogenic topoisomerase II inhibitor, in renal cell cancer with assessment of potential surrogate markers of angiogenesis. Clin Cancer Res.2000; 6(12):4697-704.
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