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Leucylarginylproline

CAS No. 133943-59-6

Leucylarginylproline( —— )

Catalog No. M21019 CAS No. 133943-59-6

Leucylarginylproline is an?inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Leucylarginylproline
  • Note
    Research use only, not for human use.
  • Brief Description
    Leucylarginylproline is an?inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM).
  • Description
    Leucylarginylproline is an?inhibitor of angiotensin-converting enzyme (ACE) (IC50 : 0.27μM).
  • In Vitro
    Intravenous injection of Leucylarginylproline (30mg/kg) causes a decrease in the blood pressure. The maximum mean blood pressure reduction (about 15 mmHg) occurrs about 2 min after the injection. Leucylarginylproline peptide reduces the blood pressure by about 15 mmHg at the fourth hour and shows a maximal reduction effect of about 35 mmHg at the eighth hour after oral administration.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    RAAS
  • Recptor
    ACE
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    133943-59-6
  • Formula Weight
    384.47
  • Molecular Formula
    C17H32N6O4
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    CC(C)CC(N)C(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Chen T L Lo Y C Hu W T et al. Microencapsulation and Modification of Synthetic Peptides of Food Proteins Reduces the Blood Pressure of Spontaneously Hypertensive Rats[J]. Journal of Agricultural and Food Chemistry 2003 51(6):1671-1675.
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